BOTOX® OAB-NC Procedure

What to Expect From BOTOX® Treatment

What happens before, during, and after your treatment appointment

Wherever you are in your overactive bladder caused by a neurologic condition (OAB-NC) treatment journey, understanding what comes next can help you better prepare for the next steps.

You and your doctor may have already decided to move forward with BOTOX® treatment for your OAB-NC, or maybe you would just like to have more information about the treatment and procedure. Either way, here’s what you can expect.

What to Expect
Before Your Appointment


When you and your doctor have decided that BOTOX® is right for you

Your doctor’s office will prepare for your appointment by:

  • Completing the necessary paperwork and contacting your insurance for pre-authorization
  • Receiving and storing your BOTOX® medication
  • Ensuring all the details are handled for a seamless treatment experience

You can prepare for your upcoming treatment appointment by:

  • Signing up to receive special BOTOX® savings
  • Watching a video about a healthcare professional’s perspective on the BOTOX® procedure
  • Scrolling down for more details about what to expect the day of your treatment

If you are still looking for more information about BOTOX® you can learn more by:

Still looking for a BOTOX® Specialist?

Treatment Procedure


What to Expect
During Your Appointment

The BOTOX® treatment procedure

BOTOX® may be given in the comfort and convenience of your doctor’s office. The entire appointment takes about an hour from start to finish.

20 minutes to prep in the comfort of your doctor’s office

10 minutes to place BOTOX® in your bladder

30 minutes for evaluation after the procedure

For a more comfortable treatment experience, your doctor will numb your bladder with a local anesthetic before administering BOTOX®

Your doctor will prescribe you antibiotics to help prevent a urinary tract infection.
You will be instructed to take them before, on, and after the day of treatment.

Watch healthcare providers and people with MS talk
about their experiences with BOTOX®.

Ongoing Retreatment

OAB caused by a neurologic condition is chronic and requires ongoing treatment

Plan on BOTOX® Retreatment

*In clinical trials, 6 weeks after treatment, people treated with BOTOX® had an average of ≈20 fewer leakage episodes per week (or ≈2.8 per day) compared to 11 fewer leakage episode per week (or ≈1.5 per day) with placebo. In clinical studies, results were measured at 2, 6, and 12 weeks, with 6 weeks being the primary time point.

Understanding Potential Side Effects

BOTOX® Safety and Side Effects

Understand the risks as well as benefits


It's always important to consider the potential side effects of any medication and equally weigh the benefits and risks with your doctor before making a decision.

The most common side effects (≥ 5% and > placebo) in clinical trials for OAB-NC were:

  • urinary tract infection
  • temporary inability to fully empty your bladder

Nearly all patients could still urinate when they needed to after BOTOX® treatment; however, there have been instances where some people temporarily could not fully empty their bladder on their own. If you have difficulty fully emptying your bladder after receiving BOTOX®, you may need to use disposable self-catheters. A self-catheter is not like the kind you see in a hospital. It is much smaller (fits in your purse or pocket), easy to use, and you use it by yourself.

You should not receive BOTOX® if you currently have a urinary tract infection (UTI) or are not willing (or able) to use a disposable self-catheter if necessary.

This list is not a complete list of possible serious side effects. Please see Important Safety Information Including Boxed Warning. Talk to an OAB Specialist familiar with BOTOX® if you have any concerns.

2 in 100 people who started BOTOX®, stopped due to side effects in clinical trials.*

*Discontinuation rate in BOTOX® pivotal trials due to adverse events: 2.3% for BOTOX® (n = 262) vs 1.1% for placebo (n = 272).

Still looking for a BOTOX® Specialist?

Frequently Asked Questions About BOTOX®